ClinicalTrialDelaysCost
$600K–$8MPerDay.
Contract negotiation takes 109 days on average.
Syntheka cuts that to 45 by placing both parties in a single workspace.
Designed for clinical operations teams at top pharmaceutical companies and academic medical centers
$3.6 Billion Lost to Email Chains and Word Documents
Before a single patient can enroll, sponsors and sites must negotiate a contract and budget. This process is the single largest bottleneck in study start-up — and the technology to solve it hasn't existed until now.
Average negotiation cycle time
Negotiation happens outside platforms
Maximum daily cost of delay
“The most important business decisions in a clinical trial are made in email threads that no audit can reconstruct.”
OneWorkspace.BothSides.RealTime.
Syntheka replaces the chaos of email, Word redlines, and Excel budgets with a single collaborative workspace. The contract and budget sit side by side. Both parties negotiate together.
Designed for Dialogue, Not Document Storage
Contract and Budget, Side by Side
See the legal agreement and the financial budget in one view. A change to an indemnification clause has a direct financial impact — Syntheka makes that connection visible.
Threaded Clause-Level Negotiation
Attach a comment to a specific contract clause or budget line item. Tag your legal team. Resolution happens in context — not scattered across 47 email threads.
Proposed changes to liability cap based on FMV.
Reviewed. These align with our 2026 guidelines.
Flexible Approvals That Match Reality
Pre-configure approval chains or loop in an ad-hoc reviewer with one click. No more forwarding emails to your boss asking "are we okay with this?"
Complete Audit Trail
An immutable, time-stamped log captures every edit, comment, and rejection — including the rationale behind each decision. Inspection-proof and GCP ready.
Built for Both Sides of the Table
Accelerate Site Activation
- Cut negotiation cycles from 109 days to 45
- Real-time dashboard across entire portfolio
- Zero version control errors — ever
- Complete audit trail eliminates risk
Finally, a Platform for You
- Build defensible budgets with FMV data
- Reduce administrative burden by 40%
- Negotiate with justification documents inline
- Free for sites invited by sponsors
The Math That Matters
Target Cycle Time Reduction
In-platform Engagement
TAM Addressable
Audit Compliance
Email Got You Here.
Syntheka Gets You to Best-in-Class.
| Before Syntheka | With Syntheka |
|---|---|
| CTA_v5_final_USE_THIS_ONE.docx | One living document, always current |
| Negotiation history scattered in inboxes | Complete history in one thread |
| 15 hours/week chasing signatures | Approvals routed automatically |
| Audit trail: "Version 3 uploaded" | Captures the "why" behind decisions |
| 109-day average cycle time | 45-day target cycle time |
Compliant. Secure. Inspection-Ready.
21 CFR Part 11
Electronic signatures and complete audit trails meeting FDA requirements.
AES-256 + TLS 1.3
Data encrypted at rest and in transit with financial-grade protocols.
SOC 2 Type II
Independent security audit verifying our commitment to data integrity.
Data Residency
US hosting with EU and APAC residency options to satisfy local laws.
Placing Agreements Together
Syntheka comes from the ancient Greek syntheke(συνθήκη), meaning “placing together.” In ancient Greece, it described treaties reached through dialogue, not dictation.
We believe clinical trial negotiation should work the same way. Two parties, placing terms together until alignment emerges. Not emailing documents into the void and hoping for the best.
Every day a contract sits in an inbox is a day a patient waits for a life-saving therapy. We're building Syntheka to close that gap.
Ready to Negotiate Faster?
Join the waitlist for early access. Be among the first clinical operations teams to replace email-driven friction with real-time collaboration.